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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09412bc00317ec884c7af39f99520927d5efc98c4a8a2aa8821b8a6137472c81' 
  AND token = 'TE2IKGHsrfMUNOmA9oRfUMKn4NbV43zv4dm9TGlEVsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}