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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e56aa93ac8ef691b586e765bea1495ffe0f0e15bc6d0b1bd4aa7e857815836' 
  AND token = 'Q0Bjp98notZq3/tnQBDk1dsmgLLdaDr89JXO2W6mhhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}