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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19254341fac17f6a54b687a385576fb8389b73b8c84c981b549827820027e595' 
  AND token = 'j7lXPl5TiPnTHkLS9Z2dmo/peiA+7U3ikUu/9F8NNkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}