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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7a8cc6ed939a440feb2a901eead33a80048d186c96b33bbb0f5cf3c8321a97c' 
  AND token = 'pI2CZqnxP0aqSWR3hEZMQ8pEP0cyllPM//In4hGuflM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}