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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e76842d2107708255a4b4b52f64362d0e74d26f4195087596c677961d71311' 
  AND token = 'Nc6hriFxPMAHY9U2ooyf3/ICBQ7Lb/UmzwRz8TsUvEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}