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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f660bd40f2195a1ed5cd8ac03361b405c1635d7180f04d77d3194ef3fe1e6156' 
  AND token = 'Y2FXoLJFs8mkyPrGh3uiATKzVuEn4fmcmDb2XaMKX+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}