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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbd8f3921369f4462c918b897c3c8dac487f1d400007278ae4aa90876c896e98' 
  AND token = 'JCOWTZQ2+94IB3gNiwDdPOfnGbjYACiBMb8MsG8kv+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}