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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b53b30e24d1a8d9eb0d67445e21ed34db50d4e11a161a78c45196aa93d76acb' 
  AND token = '/kBT9jYw8yISo3vUrOt0NxD8d1RqxPWGPiHpEw9D9rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}