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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d852560ab5d3d91c2a01adae44d8d3b2a09f6af30b99ff6cc72f119986e77d1' 
  AND token = 'W5TUSCBB84BsPfpi6lW0y/2Kk4c48yzreoj5UhydCmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}