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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3890636aeee066ebb82b5e2edaeff8e6de75474c3c47e515276657d43bb87397' 
  AND token = 'ssuOyJps2xfoDWvURPI/GiKhMcn8etcSSPq1JytygKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}