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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e57821b777f189179dfd755114a3d7427dda525e29793eda8a2453ceef08d1' 
  AND token = 'AZEejlvyDrmah8NN0WDW5/6zyXus5++1U/4Rdv8s320=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}