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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6caea51df46dfcb768219bfcf8961d5a2aaa7a6d17e96e5351af00a779fb144' 
  AND token = 'vDiM81/HsC3B56YlK1PRhUAEFAg88MAD3n50K49hA2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}