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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '816f922629529984ad158ca75cec9fc8f2569b45e7899e5563237ac883fb4040' 
  AND token = '5+woL3EeoLCCiIO2JbNlVEQs/6EAPPXh0RF6TJmakmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}