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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bee4404c1636f6ea33f0d2b4b87057c1d9fede455810215e1560ba00aef58f29' 
  AND token = 'GyzXYtS1GUwbFsKd/iS9g4Czixs3rc1WQ4PfHLstc5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}