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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd1173386120c1ddda65b249afd6eb50e6c5860589c9b9702ce3ff3554e42f5a' 
  AND token = '7P6Iwdcua9ckbrQGw2U++rNI6CemzmsmzIAHV6+gXZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}