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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7b21e3263f09bfd9f92fc16241967a7e8e1be46604c226e83fddddc9b9707ec' 
  AND token = 'E43adN8eBG/DoyK7krKFo5I5SNgzLdxay30UvdZgVlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}