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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d58d59436d24ac4c8aa3c2009d44c236d0db50a8eb1b0ba6f7d49ef9d0bf1fa' 
  AND token = 'OrOqkuQ8f+fj7G9VOwScp5JjgkzlLo0Jb43/GRj9NMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}