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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bff459d5a00e1b1fa301d175f7dc416d4ea84ae54b01977973605991e43296f' 
  AND token = 'sfy1SN5drvHP5hHDoytSkPEkIDeYTeVvb4ZzTn5AlV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}