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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b37004c9ce8d1ca7306b318853d91bfacb8edfa1a1968f3aa8d98f73a647a6d1' 
  AND token = 'eFUO79cKISLmr++HvHrsvSmSgPagbeqf344CzamiQxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}