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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499ade6bb79a4c602bfb5130aa9de54be9275733735294a101305f66e8c12176' 
  AND token = '9458rrXHo/g5KrMmG8/nUcQ/1F9fuQwh/fDgYbpR3Gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}