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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b9343c0a12c0e53f3ca54281e2c7a5f1bb511d88487ef3a95e8166e1c22b55c' 
  AND token = 'BNv5TSiGU/KZT9y3QRRPYrabBlScagTS8/4XZV2BUHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}