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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5797213c487a03f14e506f6bcb6d7e636b9fe0c4d849af58631ff7150613e0b1' 
  AND token = '21+YnK3KSaDDlbX1nDEXRylaJ7t8ZNzoUSCyJNMkeV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}