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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291e469eb0b4fff00ec34635754f6bb7285608d3068cd41e6f6a29148e9bf15c' 
  AND token = '1dQdi5lAtab14szmbDi3pbKx4QVggeKIiVOt6cYMXHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}