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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '341a3e341413f7f97a23c3b277fe6118ad5597fcc0feeef7b6614ede148624c9' 
  AND token = 'ic9aRXMxpL12nvyE+XSCqaBtRE2INRfUkJPaw8jDE90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}