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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3ffd62499d0d99fec1e51d7784a8a47e6472ee92f73846d07ad3965546ceb9c' 
  AND token = 'DC0D6cMR4hgYj+ssg3xTS2zj9EYMlHcS4hkgoTeoIIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}