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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c526f2e118d24daf03474644392981e0c15e564cbd8be4ad7d335ff9ed6ee80' 
  AND token = 'kKoGmDfgIPz5xNwyXJ5SiIWB1l2oTx4H6imUOou4xRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}