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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb34a2a36bbaf3ec4ac5478286dd0ac2f2258e34cfe641332855cee110d828d5' 
  AND token = 'z/Hq4KMVCVhax8pzuvcJRb6Qtisz1nlc/XU3Sb6oI18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}