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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0eba1fde0d1cc544ae272385fa46bf8973f3f8152440c4c21eae4ffb3e0071d' 
  AND token = 'R2m95rpT86b2dSSq9gulIgkoHmPX0ur56NrGJ+Yl1Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}