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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a4ea6bdd311ec2e8518feaf530addbd128e9f60e4b413f75d671c444b6bf805' 
  AND token = 'ifgyIWreOBgf41jaVZTn1fhrjS+fZW6wnnI1XR2hDm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}