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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42414e9a28e520a7fca92f7b926d54198d0c5145c8ca6f3df7476a4b705e50b4' 
  AND token = 'R4aOzxD29FDJOTpdmm8At6+FZnKpwjN7nfh1GjITW+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}