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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14f80249ab90babff3f7beaa5c0fe8ec33f29ec74f5bf29fb73390b915eb71e1' 
  AND token = '4RVwLO8U6HtlZ2fqu3Sjck8G9AMTeAuFxkupyj0VAN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}