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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2b42507d69183bc1f44fa4bdf950e1c0a83db568b6fbe92040a5a3af166d472' 
  AND token = 'EfDMoaui+rlYVtVKed9+W3qQJ2GblUxn6bsj7r1+uSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}