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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a8259703ef8a6f51f3772b52e01480f77121bc7dd3c8e43a923e38f7f8f0c89' 
  AND token = 'H6Xyk+MmVbhfUFNKDuoa/9+CXQDITI5yD6icKDcniZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}