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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d25040e066cc73dff03bc969ff885b9a73c5e30c43f00bf5a420df0f6385f77' 
  AND token = 'eO0brQ1m+3BGPCgUvpdAvPeL8SqbZeKdCTGeEB8ImEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}