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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d8e9efecf6a35dd1d4a23ec6cce39c6908fa9051410b282e247c0aebc635b26' 
  AND token = 'm9eMFOjqntQMKfVLoo0HtFUUocVL78r08Tw3F+yas8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}