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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e89dd6a371160bcae4dc7eab49adae3161eb67c7f8d9901d866ba0b4b08d0d0e' 
  AND token = 'J2VM47JPVOAxVeO2yR4aFxdOzVvaHxn8PRgLZ59k+0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}