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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1146c9216cbf7f7e6ca3e50a46bca59afee5bf0a7e2effb685955d59a8e98e2f' 
  AND token = 'fvYktayprEVbEvOO/4J0z0qI3rIWOqwFucasRI2Avw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}