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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '777afe15a124a0697bc0569420cc3fcae96b3092cd869b9197cc6010e65be49f' 
  AND token = 'rUlnYVm2TNjBxUNKfLwzsjjocE0GZiAu7+Q6ZJExUCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}