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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '548e26747e8d11052d279b10bdb24e8d1ef6db15e285b09ff8f15985417407ea' 
  AND token = 'LQbx53xDib8JJZX7wT0YzREz8MOU308nBWAaBzzHovY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}