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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cc1e47b292cdc07b66c22a81290cba6a33faaf95d08adb93b16238371d69b6c' 
  AND token = 'j70a25iOLskJuNXUDfjFa59Y7vlLusPUCFuaH9A3dCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}