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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dffdf6d873cbaefd91d78d6fdce8512e37a0f01afa8e5fc727cb02d8d1514823' 
  AND token = 'IXr/3/OmwPy8GNCrDeHsjylc1aoj+sClKkAQs/X7Smo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}