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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d210ff7badb2231f5f78cb9f16006e14888f1cfe333ad619550abe6b452c7f1' 
  AND token = 'qrVIrTT4AKetQmR/tyw/rRCT1k95nKKlc+Di5aHR9qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}