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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '730920a7e4a77e780ef62898337c7f59782bfcd75b0dcf6494814d0205c3f809' 
  AND token = 'r+leQ4SUme5TdJRhSHs784O0m3F/4MTzH7oDOrDeNVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}