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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a18266a07e67cb440d9a41f681d6fabcacfb31ea05d58d2193252cd75977b7' 
  AND token = 'LnPOwfTI45xHBGXFjD1OLEP7HN1moe7Y57g/ksox8Vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}