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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc43aecb359e7ede9d3e602f161f9e8e39faa1fadcad839908407f2f488998c1' 
  AND token = 'Sw5xI4G9/p5vlOHXS0gr1Z4ELzhW1lBYnVXPyH815O4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}