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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '124a181f63c363ea3c3e7aad3c817893c0034eab6a979a3597104a747a533819' 
  AND token = 'KIwtmgrV9Km5J5r0aOvpsGUGJNk0IdOgDZalzQnEk5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}