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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6990bcecdf7a9dcc4b8a78833d7777808c18442d634d7421945afdcfe98be8a1' 
  AND token = 'mOC1Kc6rrGq7p6xsoULJRwyQtMcoEmTKyBf1y+l7LVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}