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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3079fccaf84dd293cb0df0b9d95b0bd822d59a43dd996b31486afe869da3da7' 
  AND token = '21bkPNo0cjrLJWwUa2gKjcZo0eIIhw94Jcr/wpZZ4ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}