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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5f7de6138bc3e639356e2e91e8211134e1d6b3ca93e196934a4224cc70dcdc6' 
  AND token = 'Fq5GBSZ3QTwxqXHRCiGHDQ91YBsjp3CQEf6VjPUbmsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}