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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83bccf4e345124e606b1def917d5eb67f5a096019c357fbe19f414704fb91fa3' 
  AND token = 'SYaTX3Xw8x5CBHYq3NOcz6TnbX9snqClZCVrvLXWHwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}